Searchable abstracts of presentations at key conferences in endocrinology

ea0022p597 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Contribution of the molecular biology to the study of the behaviour of pituitary adenomas

Sanchez-Tejada Laura , Sanchez-Ortiga Ruth , Niveiro Maria , Peiro Gloria , Moreno Oscar , Aranda Ignacio , Alfonso Antonio A Pico

Background: There is an increasing interest to find specific prognostic markers of the aggressive behaviour of some pituitary adenomas (PA). The most studied markers have been the immunohistochemical staining for Ki-67 and p53. The aim of this study was to evaluate the relevance as possible prognostic markers of growth factors (IGF1R), angiogenic factors (VEGF and his receptor) and new genes (PTTG) versus the immunohistochemical expression of Ki-67 and p53 in PA.<p class="...